BPKMCH | ANNUAL REPORT - 2018

DEPARTMENT OF PATHOLOGY

Introduction:

Department of Pathology has been an integral part of BP Koirala Memorial Cancer Hospital, since its

inaugurat on as a Day Care Center on 11 October 1995. Our moto is to provide cut ng edge diagnost c

pathology services while achieving qualitat ve outcomes in pathology research and educat on.

Pathology services were started with rout ne laboratory tests, Fine Needle Aspirat on Cytology and Bone

marrow examinat on. Afer indoor services were started on 20^th July 1999, pathology services were also

expanded. Now we have our own separate two-storied building allocated for Department of Pathology.

Responsibilit es of the department are immense and paramount to the services of the cancer pat ent in

rendering a final diagnosis, assist in evaluat on of prognost c factors, facilitate support ve services during

treatment and help in assessment of recurrences or persistence of disease. The scope and volume of the

clinical services provided by the Pathology Department have cont nued to grow steadily in the past years.

We are very proud to be associated with longstanding excellence in pat ent care, educat on and research; and

cont nue to build on these rich tradit ons into the future.

Services:

Department of Pathology serves as a core facility for the BP Koirala Memorial Cancer Hospital and has different

units allocated for different invest gat on modalit es. Our department has been pioneer in Nepal to start Flow

cytometry, Immunohistochemistry and Cytogenet c studies, which have been regularly done in our Inst tute.

Histopathology unit: Minor and Major biopsies for histopathological examinat on and diagnosis.

Special stains, when required, are also carried out. 18% more than that of 2017.

Total Histopathology cases:

6068

Minor Biopsy:

4684

Major Biopsy:

1384

Cytopathology unit: Fine Needle Aspirat on Cytology along with USG and CT guided aspirat ons,

Exfoliat ve cytology (Cervical Papanicolau Smear, Bronchial brushing, Bronchioalveolar lavage, Urine

barbotage); Body Fluid Cytology (Pleural fluid, Peritoneal fluid, Cerebrospinal fluid) invest gat ons are

available daily.

Cervical Liquid Based Cytology:

3476

Cytology of body fluid and exfoliat ve cytology:

777

Fine needle aspirat on (FNA):

3759

Hematology unit: Rout ne Tests include Blood Hemogram, Total Leukocyte count, and Different al

count done on daily basis by fully automated five-part hematology analyzers(Sysmex XN1000).

Peripheral Blood smear examinat on; Bone

marrow aspirat on and examinat on for

HEMATOLOGY TESTS

hematological abnormalit es are available.

Total Hematology cases: 263119

Bone Marrow Aspirat on: 716

Peripheral Blood Smear: 2717

Biochemistry unit: Fully automat c Biochemical

analyzer

(Dimension RxL, Siemens) is in

operaton to carry out biochemical tests. Total

Cases: 328809

BPKMCH | ANNUAL REPORT - 2018

4. Immunoserology Unit: Fully Automated Roche ecobas 411 analyzer is being used to perform tumour

markers

Total Cases: 14601

5. Microbiology unit: Culture and sensit vity are

Immunoserology Test

performed by Bactec Culture System along

with Serological tests on a daily basis. Various

samples like blood, urine, pus, sputum, body

fluid(pleural fluid, bronchial wash, CSF, bile, etc)

and Swab culture and sensit vity tests(Total 999

cases) are performed. Special stain viz: Gram’s

Stain-120, Stain in AFB- 802, KOH Preparat on

-29, ASO t tre -107, CRP -672 and Mantoux test -

101 cases are done in 2018.

Immunohistochemistry unit: This unit was

started on

16 December

2009. Our panel

includes

16 markers, with complete breast

panel for diagnost c purposes. In 2018 a total of

769 IHCs are reported

6. Flowcytometry unit: Flow cytometry was started on 1 January 2010. Four colour BD FACS system is in

use for diagnosis of hematological and lymphoid malignancies. In 2018, 8 cases are examined.

7. Emergency Lab: Twenty four hour laboratory services are provided through the emergency lab unit

located within the premises of our department. Recently a new emergency lab is situated in the new

ward building for effect ve emergency services.

8. Plateletpheresis: A Fresenius Kabi Pheresis is under use to perform plateletpheresis and a total of 81

cases are done in 2018.

BPKMCH | ANNUAL REPORT - 2018

Academic Activities:

Being one of the prime diagnost c department, our most significant roles is in the teaching of the next

generat on of pathologists and laboratory technical staff.

Training of MD Pathology students from different Medical Colleges

Training and discussions of general and clinical pathology were delivered to BMLT, CMLT and

AMLT students.

Lectures offered on different topics to MN, BNS, BMLT,CMLT and AMLT students

Dr. Ranjan Raj Bhata: Three months training on Cytogenet c at ATREC, Mumbai (2018 Nov 12-

Feb11)

Dr. Greta Pandey: Part cipat on and oral presentat on on “ Histopathological spectrum of skin

tumor at tert ary cancer centre in Nepal” at Internat onal Society of Dermatopathology, San

Diego, California on 2018 Feb 14-15

Dr. Greta Pandey: Part cipat on in 12^th Jude Pediatric Pathology Symposium and viva forum on

8-9^th March 2018 in Singapore.

Dr. Greta Pandey, Dani Kumar Yadav and Sashi Kushawaha: Training for apheresis and

immunohistochemistry at 4^th Hospital, Hebei Medical University, Shijiazhuang, Hebei, People’s

Republic of China from 2018 Aug 13 - Sept 30^th.

Three days training sessions in Usage of RT PCR held at Department of Pathology supported by

American delegates from University of UTAH, USA.

Research and discovery are important missions for the Pathology Department. A broad spectrum of research

act vit es are carried out in the department.

In collaborat on with Berger University Norway, research on the role of S100 protein in Oral

Carcinoma is going on.

Publications:

1. Dr Sadina Shrestha: Human Papilloma Virus genotype distribut on in cervical cancer biopsies from

Nepalese Women, Infect ous Agents and Cancer 2018,13:4

2. Dr Shankar Bastakot : Angiomyolipoma; a rare ent ty in the lef adrenal gland, Journal of Pathology of

Nepal 2018, Vol 8, 1416-1418.

Human Resources:

Head of Department and Senior Consultant:

Dr. Sadina Shrestha, MD

Senior Consultant Pathologist: Dr. Chin Bahadur Pun, MD

Junior Consultant Pathologist: Dr. Ranjan Raj Bhata

Registrar:

Dr Greta Pandey, Dr Shankar Bastakot , Dr Nandita Jha, Dr Suraj Upret , Dr

Ishan Dhungana

Asistant Chief Technologist:

Mr. Asta Ram Khagi

Senior Technologists:

Mr. Shyam Sundar Rawal, Mr. Deepak Subedi , Mr. Krishna Pokharel, Mr.

Megh Raj Sapkota , Mr. Dani Kumar Yadav , Mr. Soma Kanta Baral, Mr Pradip

Hamal, Mr. Madan Pandey *.

Technologist:

Mr Rajendra Prasad Joshi, Mr. Keshav Paudel, Mr. Yubaraj Gautam, Ms Srijana

Sapkota

Technicians:

Mr. Asim Shrestha ,Mr. Manohar Shrestha, Ms. Dipa Koirala, Mr. Dipak

Chapagain, Ms.Sushila Adhikari , Mr. Sashi Kushwaha, Ms Chunu Kumari

Tamang, Mr. Gokul Bhandari, Mr Keshav Dhungana, Mr Anil Shah, Ms Binita

BPKMCH | ANNUAL REPORT - 2018

Khaitu, Ms Rabika Acharya, Mr Sandip Shah, Mr Uday K. Mandal

Helper:

Mr. Laxman Bhandari

Atendants:

Ms. Laxmi Neupane,Ms. Sita Dawadi,Ms.Buddhi M. Sunar, Ms.Kalpana

Tamang, Mr. Dhurba Gautam, Ms.Mina Tamang, Ms. Sunita Bhatarai,Ms.

Parbat Aryal, Ms Jamuna Adhikari

Future Plans

 Histopathology and cytopathology report ng expedit on through recruitment of Pathologists.

 Expansion of immunohistochemistry service and resumpt on of Frozen Sect on.

 Expansion of cytogenet cs service and establishment of infrastructure for molecular pathology lab.

 Start ng of Clinical-Pathology meet rout nely with Various Clinical Units.

 Preparat on of teaching modules for residency based programme, Observat onship and Fellowship.

 Set up computerized report ng system and central report dispatch.